2-Chloro-5-(chloromethyl)thiazole, a chemical compound with a unique molecular structure, has several intriguing properties that make it a valuable component in various industries and applications. In this article, we will explore the properties of 2-Chloro-5-(chloromethyl)thiazole and discuss its significance in different fields.
**Chemical Structure**.
2-Chloro-5-(chloromethyl)thiazole, also known as CMST, has a molecular formula of C5H4Cl2NS and a molecular weight of 184.0 g/mol. It consists of a thiazole ring with two chlorine atoms attached, one at position 2 and the other at position 5. Additionally, a chloromethyl group is linked to the thiazole ring, providing unique reactivity to the compound. The arrangement of atoms in the molecule imparts specific properties that are advantageous for various applications.
**Physical Properties**.
The physical properties of 2-Chloro-5-(chloromethyl)thiazole contribute to its versatility in different environments. CMST is a light yellow to brown liquid with a characteristic odor. It has a boiling point of approximately 193°C and a density of about 1.50 g/cm3 at room temperature. The compound is soluble in organic solvents such as acetone, ethanol, and diethyl ether but shows limited solubility in water. These physical characteristics make CMST suitable for use in solution-based processes and formulations.
**Reactivity**.
2-Chloro-5-(chloromethyl)thiazole exhibits unique reactivity due to the presence of chlorine atoms and the chloromethyl group in its molecular structure. The compound is a versatile reagent in organic synthesis, particularly in the formation of carbon-sulfur and carbon-nitrogen bonds. CMST can undergo nucleophilic substitution reactions to introduce thiazole moieties into various molecules, making it a valuable building block in the synthesis of pharmaceuticals, agrochemicals, and specialty chemicals.
**Biological Activities**.
The presence of a thiazole ring in 2-Chloro-5-(chloromethyl)thiazole imparts interesting biological activities to the compound. Thiazoles are known for their antimicrobial, antifungal, and antiparasitic properties, making CMST a potential candidate for developing new drugs and pesticides. Recent studies have shown promising results in the use of thiazole derivatives, including CMST, as antimicrobial agents against drug-resistant pathogens. The biological activities of 2-Chloro-5-(chloromethyl)thiazole are an area of active research for exploring its therapeutic potential.
**Industrial Applications**.
The properties of 2-Chloro-5-(chloromethyl)thiazole make it a versatile compound with diverse industrial applications. CMST is used as a key intermediate in the synthesis of pharmaceuticals, such as antifungal agents and antibacterial drugs. It is also employed in the production of agrochemicals for crop protection and pest control. Additionally, 2-Chloro-5-(chloromethyl)thiazole finds application in the manufacturing of specialty chemicals, including dyes, pigments, and polymers. The compound's reactivity and biological activities make it a valuable ingredient in various industrial processes.
In conclusion, 2-Chloro-5-(chloromethyl)thiazole possesses unique properties that make it a versatile compound with significant potential in pharmaceutical, agrochemical, and specialty chemical industries. Its chemical structure, physical properties, reactivity, biological activities, and industrial applications highlight the importance of CMST in various fields. Further research and exploration of 2-Chloro-5-(chloromethyl)thiazole may uncover additional uses and advantages of this intriguing compound.
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